The salience network operates through a cortico-striatal-thalamic loop in which…

The salience network operates through a cortico-striatal-thalamic loop in which the dorsal anterior cingulate, anterior insula, dorsal striatum and mediodorsal thalamus together regulate cognitive control and are implicated across psychiatric illness.

{
  "n": 0,
  "doi": "10.3389/fnsys.2016.00104",
  "claim": "The salience network operates through a cortico-striatal-thalamic loop in which the dorsal anterior cingulate, anterior insula, dorsal striatum and mediodorsal thalamus together regulate cognitive control and are implicated across psychiatric illness.",
  "cite_key": "Peters2016",
  "evidence": "Review of fMRI and lesion data implicating SN cortico-striato-thalamo-cortical loop in psychiatric disorders.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "human salience network (clinical review)",
  "source_cluster_id": "cluster_05",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "In addition to cortical nodes of the SN, the network's associated subcortical structures, including the dorsal striatum, mediodorsal thalamus and dopaminergic brainstem nuclei, comprise a discrete regulatory loop circuit.",
  "replication_evidence_dois": [
    "10.3389/fnsys.2016.00104",
    "10.1016/j.brainresbull.2008.09.013"
  ],
  "effect_size_source_sentence": null
}

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