Details

scope
mammalian thalamocortical circuits (review)
claim_text
Higher-order thalamic relays (e.g., pulvinar) receive layer-5 driver input from cortex and form transthalamic corticocortical pathways that parallel direct cortico-cortical connections.
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-06
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
study_system
mammalian thalamocortical circuits (review)
section_title
Thalamic Feedback: Closing the Loop
evidence_summary
Synthesis of anatomical/physiological evidence for layer-5 driver-defined transthalamic pathways carrying corticocortical messages, often as efference-copy branches of motor axons.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-06
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1038/nn.4269",
  "claim": "Higher-order thalamic relays (e.g., pulvinar) receive layer-5 driver input from cortex and form transthalamic corticocortical pathways that parallel direct cortico-cortical connections.",
  "cite_key": "Sherman2016",
  "evidence": "Synthesis of anatomical/physiological evidence for layer-5 driver-defined transthalamic pathways carrying corticocortical messages, often as efference-copy branches of motor axons.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mammalian thalamocortical circuits (review)",
  "source_cluster_id": "cluster_05",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Different driver sources reveal two types of thalamic relays: first order relays receive subcortical driver input (for example, retinal input to the lateral geniculate nucleus), whereas higher order relays (for example, pulvinar) receive driver input from layer 5 of cortex and participate in cortico-thalamo-cortical (or transthalamic) circuits.",
  "replication_evidence_dois": [
    "10.1098/rstb.2002.1161",
    "10.1038/nn.2449",
    "10.1152/jn.00429.2011"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-ef147548c82a"
]
source_span
Different driver sources reveal two types of thalamic relays: first order relays receive subcortical driver input (for example, retinal input to the lateral geniculate nucleus), whereas higher order relays (for example, pulvinar) receive driver input from layer 5 of cortex and participate in cortico-thalamo-cortical (or transthalamic) circuits.
evidence_refs
[
  {
    "ref": "paper:paper-ef147548c82a"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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