In a rat S1 barrel column, every excitatory neuron type receives substantial th…

{
  "n": 580,
  "doi": "10.1093/cercor/bhq069",
  "claim": "In a rat S1 barrel column, every excitatory neuron type receives substantial thalamocortical innervation (~90–580 boutons per neuron); thick-tufted L5 pyramidal cells receive comparable VPM and POm bouton numbers (~300 each).",
  "cite_key": "Meyer2010",
  "evidence": "Synaptophysin-EGFP labeling combined with reconstructed biocytin-filled neurons quantifying VPM/POm boutons onto each cell class in rat S1.",
  "effect_size": "~300 VPM boutons + ~300 POm boutons per L5 thick-tufted pyramidal neuron",
  "text_access": "fulltext",
  "study_system": "rat S1 barrel column (cell-type-specific bouton quantification)",
  "source_cluster_id": "cluster_05",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "We found that all types of excitatory neurons potentially receive substantial TC input (90-580 boutons per neuron); 2) pyramidal neurons in L3-L6 receive dual TC input from both VPM and POm that is potentially of equal magnitude for thick-tufted L5 pyramidal neurons (ca. 300 boutons each from VPM and POm); 3) L3, L4, and L5 pyramidal neurons have multiple (2-4) subcellular TC innervation domains that match the dendritic compartments of pyramidal cells; and 4) a subtype of thick-tufted L5 pyramidal neurons has an additional VPM innervation domain in L4.",
  "replication_evidence_dois": [
    "10.1093/cercor/bhn259",
    "10.7554/elife.44158"
  ],
  "effect_size_source_sentence": "pyramidal neurons in L3-L6 receive dual TC input from both VPM and POm that is potentially of equal magnitude for thick-tufted L5 pyramidal neurons (ca. 300 boutons each from VPM and POm)"
}

[
  "paper:paper-e5d5db2e3c24"
]

We found that all types of excitatory neurons potentially receive substantial TC input (90-580 boutons per neuron); 2) pyramidal neurons in L3-L6 receive dual TC input from both VPM and POm that is potentially of equal magnitude for thick-tufted L5 pyramidal neurons (ca. 300 boutons each from VPM and POm); 3) L3, L4, and L5 pyramidal neurons have multiple (2-4) subcellular TC innervation domains that match the dendr...

[
  {
    "ref": "paper:paper-e5d5db2e3c24"
  }
]

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