Details

scope
primate mediodorsal thalamus / PFC (review)
claim_text
The mediodorsal thalamus is a higher-order relay of prefrontal cortex, important for trial-by-trial associative learning and decision-making rather than retention of stable information.
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-06
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
Recent evidence from monkey models of cognition shows that the magnocellular subdivision of the mediodorsal thalamus (MDmc) is more critical for learning new information than for retention of previously acquired information.
study_system
primate mediodorsal thalamus / PFC (review)
section_title
Thalamic Feedback: Closing the Loop
evidence_summary
Review of monkey lesion/inactivation and electrophysiology data positioning MD as a higher-order PFC relay with cortico-thalamo-cortical pathways carrying layer-5 drivers.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-06
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.neubiorev.2015.03.001",
  "claim": "The mediodorsal thalamus is a higher-order relay of prefrontal cortex, important for trial-by-trial associative learning and decision-making rather than retention of stable information.",
  "cite_key": "Mitchell2015",
  "evidence": "Review of monkey lesion/inactivation and electrophysiology data positioning MD as a higher-order PFC relay with cortico-thalamo-cortical pathways carrying layer-5 drivers.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "primate mediodorsal thalamus / PFC (review)",
  "source_cluster_id": "cluster_05",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Recent evidence from monkey models of cognition shows that the magnocellular subdivision of the mediodorsal thalamus (MDmc) is more critical for learning new information than for retention of previously acquired information.",
  "replication_evidence_dois": [
    "10.1038/nature22073",
    "10.1038/nn.4568",
    "10.1038/nature22324"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-c4fcf09e87a4"
]
evidence_refs
[
  {
    "ref": "paper:paper-c4fcf09e87a4"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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