A diffuse calbindin-immunoreactive matrix projects to superficial cortical laye…

A diffuse calbindin-immunoreactive matrix projects to superficial cortical layers (across area boundaries), while a parvalbumin core projects topographically to middle layers; matrix neurons disperse activity to synchronize specific and non-specific thalamocortical elements.

{
  "n": 0,
  "doi": "10.1016/s0166-2236(00)01922-6",
  "claim": "A diffuse calbindin-immunoreactive matrix projects to superficial cortical layers (across area boundaries), while a parvalbumin core projects topographically to middle layers; matrix neurons disperse activity to synchronize specific and non-specific thalamocortical elements.",
  "cite_key": "Jones2001",
  "evidence": "Anatomical/physiological framework for matrix vs core thalamocortical projections and their role in coherent thalamocortical activity.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "primate thalamus (review)",
  "source_cluster_id": "cluster_05",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "A matrix of calbindin-immunoreactive neurons extends throughout the thalamus and projects to superficial layers of cortex over wide areas, unconstrained by boundaries between areas.",
  "replication_evidence_dois": [
    "10.1093/cercor/bhn259",
    "10.1523/jneurosci.3231-12.2012",
    "10.1016/j.neuron.2024.04.019"
  ],
  "effect_size_source_sentence": null
}

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