Identify a functional cortico-cerebellar loop and suggest the cerebellar cortex…

{
  "n": null,
  "doi": "10.1038/s41593-023-01453-x",
  "claim": "Identify a functional cortico-cerebellar loop and suggest the cerebellar cortex selectively establishes reciprocal cortico-cerebellar communications to orchestrate motor planning.",
  "cite_key": "Zhu2023",
  "evidence": "The neocortex and cerebellum interact to mediate cognitive functions. It remains unknown how the two structures organize into functional networks to mediate specific behaviors. Here we delineate activity supporting motor planning in relation to the mesoscale cortico-cerebellar connectome. In mice planning directional licking based on short-term memory, preparatory activity instructing future movement depends on the anterior lateral motor cortex (ALM) and the cerebellum. Transneuronal tracing rev...",
  "effect_size": "Six of them were subsequently used to localize the 4 × 4 mm grid for optogenetic mapping experiments (Extended Data Fig.).",
  "text_access": "fulltext",
  "study_system": "mouse; motor cortex, ALM, neocortex; Nature neuroscience",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "These results identify a functional cortico-cerebellar loop and suggest the cerebellar cortex selectively establishes reciprocal cortico-cerebellar communications to orchestrate motor planning.",
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  "effect_size_source_sentence": "Six of them were subsequently used to localize the 4 × 4 mm grid for optogenetic mapping experiments (Extended Data Fig.)."
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The neocortex and cerebellum interact to mediate cognitive functions. It remains unknown how the two structures organize into functional networks to mediate specific behaviors. Here we delineate activity supporting motor planning in relation to the mesoscale cortico-cerebellar connectome. In mice planning directional licking based on short-term memory, preparatory activity instructing future movement depends on the anterior lateral motor cortex (ALM) and the cerebellum. Transneuronal tracing rev...