Details

scope
mouse V1 superficial layers; large-scale recurrent network model constrained by paired-recording data and compared with in vivo two-photon recordings
claim_text
A feature-binding excitatory subnetwork — rather than a pure like-to-like wiring rule — best reproduces in vivo facilitatory plaid responses in mouse V1, implying recurrent E→E connections combine multiple feedforward tuning channels.
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
effect_size
Feature-binding scheme reproduces selective amplification of plaid responses not captured by like-to-like alone
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-05-horizontal
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
By comparing predictions from large scale computational models with in vivo recordings of visual representations in mouse V1, we found that responses to plaid stimuli were best explained by assuming feature binding connectivity.
study_system
mouse V1 superficial layers; large-scale recurrent network model constrained by paired-recording data and compared with in vivo two-photon recordings
section_title
5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay
evidence_summary
Network simulations of mouse V1 superficial layers under like-to-like vs feature-binding wiring constrained by paired-recording statistics; compared with in vivo two-photon recordings of plaid responses.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single_study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-05-horizontal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1371/journal.pcbi.1005888",
  "claim": "A feature-binding excitatory subnetwork — rather than a pure like-to-like wiring rule — best reproduces in vivo facilitatory plaid responses in mouse V1, implying recurrent E→E connections combine multiple feedforward tuning channels.",
  "cite_key": "Muir2017",
  "evidence": "Network simulations of mouse V1 superficial layers under like-to-like vs feature-binding wiring constrained by paired-recording statistics; compared with in vivo two-photon recordings of plaid responses.",
  "effect_size": "Feature-binding scheme reproduces selective amplification of plaid responses not captured by like-to-like alone",
  "text_access": "abstract_only",
  "study_system": "mouse V1 superficial layers; large-scale recurrent network model constrained by paired-recording data and compared with in vivo two-photon recordings",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "By comparing predictions from large scale computational models with in vivo recordings of visual representations in mouse V1, we found that responses to plaid stimuli were best explained by assuming feature binding connectivity.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Unlike under the like-to-like scheme, selective amplification within feature-binding excitatory subnetworks replicated experimentally observed facilitatory responses to plaid stimuli; explained selective plaid responses not predicted by grating selectivity; and was consistent with broad anatomical selectivity observed in mouse V1."
}
source_refs
[
  "paper:paper-8d890b2475da"
]
evidence_refs
[
  {
    "ref": "paper:paper-8d890b2475da"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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