Details

scope
mouse somatosensory barrel cortex, L2 pyramidal neurons; in vivo two-photon-targeted multi-patch recordings
claim_text
In vivo two-photon-targeted multi-patch recordings in mouse barrel cortex L2 reveal sparse pyramidal-to-pyramidal connectivity (6.7%) with overrepresented bidirectional pairs and small-amplitude unitary EPSPs.
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
effect_size
6.7% connection probability; majority of EPSPs <0.5 mV; 22% failure rate
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-05-horizontal
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
We report that pyramidal neurons form a sparsely connected (6.7% connectivity) network with an overrepresentation of bidirectional connections.
study_system
mouse somatosensory barrel cortex, L2 pyramidal neurons; in vivo two-photon-targeted multi-patch recordings
section_title
5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay
evidence_summary
Two-photon-targeted whole-cell recordings (2–4 cells simultaneously) from neighbouring L2 pyramidal neurons in mouse somatosensory barrel cortex, in vivo.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-05-horizontal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.celrep.2015.11.011",
  "claim": "In vivo two-photon-targeted multi-patch recordings in mouse barrel cortex L2 reveal sparse pyramidal-to-pyramidal connectivity (6.7%) with overrepresented bidirectional pairs and small-amplitude unitary EPSPs.",
  "cite_key": "Jouhanneau2015",
  "evidence": "Two-photon-targeted whole-cell recordings (2–4 cells simultaneously) from neighbouring L2 pyramidal neurons in mouse somatosensory barrel cortex, in vivo.",
  "effect_size": "6.7% connection probability; majority of EPSPs <0.5 mV; 22% failure rate",
  "text_access": "abstract_only",
  "study_system": "mouse somatosensory barrel cortex, L2 pyramidal neurons; in vivo two-photon-targeted multi-patch recordings",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "We report that pyramidal neurons form a sparsely connected (6.7% connectivity) network with an overrepresentation of bidirectional connections.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/nature09880",
    "10.7554/eLife.37349"
  ],
  "effect_size_source_sentence": "The majority of unitary excitatory postsynaptic potentials were small in amplitude (<0.5 mV), with a small minority >1 mV."
}
source_refs
[
  "paper:paper-6d3d01cb91a6"
]
evidence_refs
[
  {
    "ref": "paper:paper-6d3d01cb91a6"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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