Details

scope
mouse cortex (motor) and other brain regions; whole-brain single-neuron axonal reconstruction at scale
claim_text
High-throughput whole-brain reconstruction of more than 1,000 mouse projection neurons defines new cortical projection-neuron subtypes and reveals previously unknown organizing principles of long-range axonal targeting.
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
effect_size
>1000 reconstructed neurons; >85 m of axonal length
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-05-horizontal
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
Axonal shapes revealed previously unknown subtypes of projection neurons and suggest organizational principles of long-range connectivity.
study_system
mouse cortex (motor) and other brain regions; whole-brain single-neuron axonal reconstruction at scale
section_title
5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay
evidence_summary
Imaging and reconstruction of >1,000 single projection neurons in mouse motor cortex, thalamus, subiculum and hypothalamus using fluorescence micro-optical sectioning tomography.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single_study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-05-horizontal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.cell.2019.07.042",
  "claim": "High-throughput whole-brain reconstruction of more than 1,000 mouse projection neurons defines new cortical projection-neuron subtypes and reveals previously unknown organizing principles of long-range axonal targeting.",
  "cite_key": "Winnubst2019",
  "evidence": "Imaging and reconstruction of >1,000 single projection neurons in mouse motor cortex, thalamus, subiculum and hypothalamus using fluorescence micro-optical sectioning tomography.",
  "effect_size": ">1000 reconstructed neurons; >85 m of axonal length",
  "text_access": "abstract_only",
  "study_system": "mouse cortex (motor) and other brain regions; whole-brain single-neuron axonal reconstruction at scale",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "Axonal shapes revealed previously unknown subtypes of projection neurons and suggest organizational principles of long-range connectivity.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Together, the reconstructed neurons constitute more than 85 meters of axonal length and are available in a searchable online database."
}
source_refs
[
  "paper:041efce6-fc13-4416-8aca-e196f82f3d70"
]
evidence_refs
[
  {
    "ref": "paper:041efce6-fc13-4416-8aca-e196f82f3d70"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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