Details

scope
review of mouse fate-mapping
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
effect_size
100% VIP from CGE; ~100% PV/SST from MGE/POA
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-05-electrophysiology
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
The MGE and adjacent POA generate virtually all interneurons in the SST+ and PV+ classes, whereas the CGE produces all VIP+ and CCK+ cortical interneurons along with several other less abundant types.
study_system
review of mouse fate-mapping
section_title
Intrinsic Electrophysiology
evidence_summary
review of fate-mapping + lineage-tracing studies
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-05-electrophysiology
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
All cortical VIP+ interneurons originate from the caudal ganglionic eminence (CGE), whereas the MGE and adjacent POA generate essentially all SST+ and PV+ interneurons — establishing a hard developmental separation that constrains the VIP class's adult intrinsic-electrophysiology profile and 5HT3aR expression.
raw_fields
{
  "n": null,
  "doi": "10.1016/j.neuron.2018.10.009",
  "claim": "All cortical VIP+ interneurons originate from the caudal ganglionic eminence (CGE), whereas the MGE and adjacent POA generate essentially all SST+ and PV+ interneurons — establishing a hard developmental separation that constrains the VIP class's adult intrinsic-electrophysiology profile and 5HT3aR expression.",
  "title": null,
  "cite_key": "Lim2018",
  "evidence": "review of fate-mapping + lineage-tracing studies",
  "effect_size": "100% VIP from CGE; ~100% PV/SST from MGE/POA",
  "text_access": "fulltext",
  "study_system": "review of mouse fate-mapping",
  "_source_cluster": "cluster_04_intrinsic_electrophysiology",
  "replication_status": "replicated",
  "_source_cluster_index": 65,
  "claim_source_sentence": "The MGE and adjacent POA generate virtually all interneurons in the SST+ and PV+ classes, whereas the CGE produces all VIP+ and CCK+ cortical interneurons along with several other less abundant types.",
  "replication_evidence_dois": [
    "10.1093/cercor/bhp310",
    "10.1002/dneu.20853"
  ],
  "effect_size_source_sentence": "The MGE and adjacent POA generate virtually all interneurons in the SST+ and PV+ classes, whereas the CGE produces all VIP+ and CCK+ cortical interneurons."
}
source_refs
[
  "paper:paper-11e0bb0a904f"
]
evidence_refs
[
  {
    "ref": "paper:paper-11e0bb0a904f"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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