Details

scope
cross-species M1 multi-modal atlas (human, marmoset, mouse)
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
effect_size
qualitative — more Vip consensus types preserved between human/marmoset than human/mouse
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-05-electrophysiology
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
More consensus clusters could be resolved by pairwise alignment between humans and marmosets than between either of these primates and mice, particularly for Vip subtypes
study_system
cross-species M1 multi-modal atlas (human, marmoset, mouse)
section_title
Intrinsic Electrophysiology
evidence_summary
multi-omic atlas (snRNA-seq, snATAC-seq, snmC-seq2) of M1 across human, marmoset, mouse; multi-modal alignment of consensus clusters
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-05-electrophysiology
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
Cross-species comparative motor cortex taxonomy (BICCN) shows that Vip GABAergic subtypes are markedly more diversified between humans/marmosets and mice than between primates, indicating species-specific expansion of the VIP transcriptomic landscape that frames cross-species comparisons of VIP intrinsic electrophysiology.
raw_fields
{
  "n": null,
  "doi": "10.1038/s41586-021-03465-8",
  "claim": "Cross-species comparative motor cortex taxonomy (BICCN) shows that Vip GABAergic subtypes are markedly more diversified between humans/marmosets and mice than between primates, indicating species-specific expansion of the VIP transcriptomic landscape that frames cross-species comparisons of VIP intrinsic electrophysiology.",
  "title": null,
  "cite_key": "Bakken2021a",
  "evidence": "multi-omic atlas (snRNA-seq, snATAC-seq, snmC-seq2) of M1 across human, marmoset, mouse; multi-modal alignment of consensus clusters",
  "effect_size": "qualitative — more Vip consensus types preserved between human/marmoset than human/mouse",
  "text_access": "fulltext",
  "study_system": "cross-species M1 multi-modal atlas (human, marmoset, mouse)",
  "_source_cluster": "cluster_04_intrinsic_electrophysiology",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 13,
  "claim_source_sentence": "More consensus clusters could be resolved by pairwise alignment between humans and marmosets than between either of these primates and mice, particularly for Vip subtypes",
  "replication_evidence_dois": [
    "10.1038/s41586-020-2907-3",
    "10.1126/science.adf6484"
  ],
  "effect_size_source_sentence": "More consensus clusters could be resolved by pairwise alignment between humans and marmosets than between either of these primates and mice, particularly for Vip subtypes"
}
source_refs
[
  "paper:paper-pm-34616062"
]
evidence_refs
[
  {
    "ref": "paper:paper-pm-34616062"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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