Details

scope
mice lgn ()
claim_text
We report that genes that are normally enriched in dLGN, but not LP during development are preferentially downregulated in dLGN following monocular enucleation.
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
effect_size
se (Sigma‐Aldrich) and cut to 200 μm coronal slices using a vibrat
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-06
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
We report that genes that are normally enriched in dLGN, but not LP during development are preferentially downregulated in dLGN following monocular enucleation.
study_system
mice lgn ()
section_title
Thalamic Feedback: Closing the Loop
evidence_summary
PubMed-indexed paper 'Cross-hierarchical plasticity of corticofugal projections to dLGN after neonatal monocular enucleation.' (PMID 35078267); content extracted from fulltext.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-06
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1002/cne.25304",
  "claim": "We report that genes that are normally enriched in dLGN, but not LP during development are preferentially downregulated in dLGN following monocular enucleation.",
  "cite_key": "Giasafaki2022",
  "evidence": "PubMed-indexed paper 'Cross-hierarchical plasticity of corticofugal projections to dLGN after neonatal monocular enucleation.' (PMID 35078267); content extracted from fulltext.",
  "effect_size": "se (Sigma‐Aldrich) and cut to 200 μm coronal slices using a vibrat",
  "text_access": "fulltext",
  "study_system": "mice lgn ()",
  "source_cluster_id": "cluster_05",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We report that genes that are normally enriched in dLGN, but not LP during development are preferentially downregulated in dLGN following monocular enucleation.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Brains were dissected in RNase‐free conditions, embedded in low‐melting point agarose (Sigma‐Aldrich) and cut to 200 μm coronal slices using a vibrating microtome (Leica VT1000S)."
}
source_refs
[
  "paper:paper-f353a07741e4"
]
evidence_refs
[
  {
    "ref": "paper:paper-f353a07741e4"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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