Imaging across mouse motor cortex during a delayed whisker-based object-localiz…

Imaging across mouse motor cortex during a delayed whisker-based object-localization task shows that delay-period preparatory activity is spatially localized to the anterior lateral motor cortex (ALM), while sensation-related activity is represented by more posterior/vibrissal motor cortex — mapping cortico-cortical functional segregation across mouse motor cortex.

{
  "n": null,
  "doi": "10.1016/j.neuron.2017.05.005",
  "claim": "Imaging across mouse motor cortex during a delayed whisker-based object-localization task shows that delay-period preparatory activity is spatially localized to the anterior lateral motor cortex (ALM), while sensation-related activity is represented by more posterior/vibrissal motor cortex — mapping cortico-cortical functional segregation across mouse motor cortex.",
  "cite_key": "Chen2017",
  "evidence": "Wide-field and two-photon calcium imaging across mouse motor cortex during whisker-based object localization with delayed directional licking response.",
  "effect_size": "Delay-period preparatory activity localized to ALM; sensation-related activity localized to vibrissal motor cortex; outcome-related activity widely distributed.",
  "text_access": "abstract_only",
  "study_system": "Mouse motor cortex; calcium imaging in behaving mice.",
  "argument_role": "supporting",
  "replication_status": "not_yet",
  "claim_source_sentence": "Preparatory activity appeared first in deep layers of ALM, seconds before the behavioral response, and remained localized to ALM until the behavioral response.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "During tactile sensation and the delay epoch, object location was represented in motor cortex areas that are medial and posterior relative to ALM, including vibrissal motor cortex."
}

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