Details
- scope
- mouse barrel cortex (S1) L2/3, awake, all-optical two-photon, behavioral detection task
- claim_text
- In mouse barrel cortex L2/3, two-photon all-optical activation of ensembles as small as ~14 pyramidal neurons is sufficient for trained mice to detect cortical activation, placing a lower bound on perceptual cortical activity.
- section_id
- section_05
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
- effect_size
- ~14 L2/3 pyramidal neurons sufficient for behavioral detection
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-05-horizontal
- source_kind
- review_finding
- source_path
- evidence/section_05_evidence_package.json
- source_span
- By precisely titrating the number of neurons stimulated, we demonstrate that the lower bound for perception of cortical activity is ~14 pyramidal neurons.
- study_system
- mouse barrel cortex (S1) L2/3, awake, all-optical two-photon, behavioral detection task
- section_title
- 5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay
- evidence_summary
- All-optical (two-photon C1V1 photostimulation + GCaMP6s imaging) targeting of L2/3 pyramidal subsets (200, 100 and smaller numbers) in awake mice trained to report cortical activation; performance measured against catch trials.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- single_study
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-05-horizontal
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": 12, "doi": "10.7554/elife.58889", "claim": "In mouse barrel cortex L2/3, two-photon all-optical activation of ensembles as small as ~14 pyramidal neurons is sufficient for trained mice to detect cortical activation, placing a lower bound on perceptual cortical activity.", "cite_key": "Dalgleish2020", "evidence": "All-optical (two-photon C1V1 photostimulation + GCaMP6s imaging) targeting of L2/3 pyramidal subsets (200, 100 and smaller numbers) in awake mice trained to report cortical activation; performance measured against catch trials.", "effect_size": "~14 L2/3 pyramidal neurons sufficient for behavioral detection", "text_access": "fulltext", "study_system": "mouse barrel cortex (S1) L2/3, awake, all-optical two-photon, behavioral detection task", "argument_role": "supporting", "replication_status": "single_study", "claim_source_sentence": "By precisely titrating the number of neurons stimulated, we demonstrate that the lower bound for perception of cortical activity is ~14 pyramidal neurons.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "By precisely titrating the number of neurons stimulated, we demonstrate that the lower bound for perception of cortical activity is ~14 pyramidal neurons." }- source_refs
[ "paper:paper-d2118dd5013a" ]
- evidence_refs
[ { "ref": "paper:paper-d2118dd5013a" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }