Single-cell-initiated, monosynaptically restricted rabies tracing combined with…

Single-cell-initiated, monosynaptically restricted rabies tracing combined with in vivo GCaMP imaging shows that L2/3 mouse V1 pyramidal neurons receive presynaptic inputs that often form layer-specific functional modules — in roughly one-third of cases locked to the postsynaptic direction preference, in others feature-variant across layers.

{
  "n": 0,
  "doi": "10.1126/science.aab1687",
  "claim": "Single-cell-initiated, monosynaptically restricted rabies tracing combined with in vivo GCaMP imaging shows that L2/3 mouse V1 pyramidal neurons receive presynaptic inputs that often form layer-specific functional modules — in roughly one-third of cases locked to the postsynaptic direction preference, in others feature-variant across layers.",
  "cite_key": "Wertz2015",
  "evidence": "Single-cell rabies tracing with GCaMP6s in mouse V1 L2/3 pyramidal neurons; two-photon imaging of motion-evoked responses across layers.",
  "effect_size": "~1/3 feature-locked networks; remainder feature-variant",
  "text_access": "abstract_only",
  "study_system": "mouse V1; single-cell-initiated monosynaptic rabies tracing + in vivo two-photon imaging",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "In one-third of the networks, the layer modules were locked to the direction preference of the postsynaptic neuron, whereas for other networks the direction preference varied by layer.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "In one-third of the networks, the layer modules were locked to the direction preference of the postsynaptic neuron, whereas for other networks the direction preference varied by layer."
}

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