Details

scope
Mouse visual cortex (V1 → LM, AL, PM); 2P bouton imaging
section_id
section_08
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
effect_size
Target-specific match driven by both higher density and higher response amplitude of matched boutons; effect also present for L5-only projections and HVA→HVA projections (qualitative).
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
source_span
We found that visual preferences of presynaptic boutons in each area were distinct and matched the average preferences of recipient neurons.
study_system
Mouse visual cortex (V1 → LM, AL, PM); 2P bouton imaging
section_title
8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
evidence_summary
Two-photon calcium imaging of V1 axons in LM, AL, and PM during stimulus presentation; comparison of bouton vs cell-body tuning distributions.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replicated
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
V1 axonal projections to mouse higher visual areas (LM, AL, PM) carry functionally target-specific signals: bouton visual preferences in each target area match the average preferences of the recipient population, exceeding what local V1 organization predicts.
raw_fields
{
  "n": null,
  "doi": "10.1038/nn.3300",
  "claim": "V1 axonal projections to mouse higher visual areas (LM, AL, PM) carry functionally target-specific signals: bouton visual preferences in each target area match the average preferences of the recipient population, exceeding what local V1 organization predicts.",
  "cite_key": "Glickfeld2013",
  "evidence": "Two-photon calcium imaging of V1 axons in LM, AL, and PM during stimulus presentation; comparison of bouton vs cell-body tuning distributions.",
  "effect_size": "Target-specific match driven by both higher density and higher response amplitude of matched boutons; effect also present for L5-only projections and HVA→HVA projections (qualitative).",
  "text_access": "abstract_only",
  "study_system": "Mouse visual cortex (V1 → LM, AL, PM); 2P bouton imaging",
  "argument_role": "supporting",
  "replication_status": "replicated",
  "claim_source_sentence": "We found that visual preferences of presynaptic boutons in each area were distinct and matched the average preferences of recipient neurons.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/s41586-025-08840-3"
  ],
  "effect_size_source_sentence": "This specificity could not be explained by organization within V1 and instead was due to both a greater density and greater response amplitude of functionally matched boutons."
}
source_refs
[
  "paper:paper-032c4af7487d"
]
evidence_refs
[
  {
    "ref": "paper:paper-032c4af7487d"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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