Details

scope
review of rodent and primate GPe cell-type and circuit literature
claim_text
Modern molecular and physiological evidence positions the GPe not as a simple indirect-pathway relay but as a hub with widespread projections to all basal ganglia nuclei, with multiple neuron classes performing distinct roles.
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
effect_size
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-05
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
study_system
review of rodent and primate GPe cell-type and circuit literature
section_title
Pallidal Organization and the Disinhibition Principle
evidence_summary
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-05
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1111/ejn.13196",
  "claim": "Modern molecular and physiological evidence positions the GPe not as a simple indirect-pathway relay but as a hub with widespread projections to all basal ganglia nuclei, with multiple neuron classes performing distinct roles.",
  "cite_key": "Hegeman2016",
  "evidence": "",
  "effect_size": "",
  "text_access": "fulltext",
  "study_system": "review of rodent and primate GPe cell-type and circuit literature",
  "source_cluster_id": "cluster_04",
  "replication_status": "replicated",
  "claim_source_sentence": "Neurons in the second category—'arkypallidal' GPe neurons—exhibit slower and more irregular firing rates in vivo ( Abdi et al. , 2015 ; Dodson et al. , 2015 ), project heavily to the dorsal striatum (dStr), and constitute ~25% of all GPe neurons.",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2012.04.027",
    "10.1523/jneurosci.4672-14.2015"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-afc4c9ca3660"
]
source_span
Neurons in the second category—'arkypallidal' GPe neurons—exhibit slower and more irregular firing rates in vivo ( Abdi et al. , 2015 ; Dodson et al. , 2015 ), project heavily to the dorsal striatum (dStr), and constitute ~25% of all GPe neurons.
evidence_refs
[
  {
    "ref": "paper:paper-afc4c9ca3660"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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