- raw_fields
{
"n": 0,
"doi": "10.1523/jneurosci.2731-17.2018",
"claim": "Excitatory inputs to layer 5 cortico-PAG neurons in mPFC arise primarily from layer 2/3 and are significantly reduced following chronic constriction injury in mice.",
"cite_key": "Cheriyan2018",
"evidence": "Laser scanning photostimulation of caged glutamate combined with whole-cell recordings was used to map local cortical circuits onto retrogradely labeled cortico-PAG neurons in layer 5 of mouse mPFC (prelimbic and infralimbic) in brain slices from male mice with chronic constriction injury.",
"effect_size": "",
"text_access": "abstract_only",
"study_system": "mouse mPFC (PL/IL) laser scanning photostimulation with whole-cell recording",
"argument_role": "supporting",
"replication_status": "novel",
"claim_source_sentence": "Circuit mapping showed that excitatory inputs to L5 CP neurons in both PL and IL arose primarily from layer 2/3 (L2/3) and were significantly reduced in CCI mice.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": ""
}- source_refs
[
"paper:paper-31e111866efb"
]
- evidence_refs
[
{
"ref": "paper:paper-31e111866efb"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}- evidence_summary
Laser scanning photostimulation of caged glutamate combined with whole-cell recordings was used to map local cortical circuits onto retrogradely labeled cortico-PAG neurons in layer 5 of mouse mPFC (prelimbic and infralimbic) in brain slices from male mice with chronic constriction injury.