Details

scope
mouse V1, anterograde AAV tracing, tangential sections
claim_text
Long-range horizontal axonal projections in Layer 1 of mouse V1 terminate preferentially in M2 muscarinic acetylcholine receptor-negative interpatches, with significantly higher density than in M2+ patches.
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
effect_size
L1 horizontal projections to M2− interpatches significantly denser than to M2+ patches (KS test p = 5.7e-04, n = 12 ROIs)
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-05-horizontal
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
We found that in L1 projections, contained in sections 1 and 2, to M2− interpatches were significantly (= 5.7e-04;= 12) denser than to M2+ patches ().
study_system
mouse V1, anterograde AAV tracing, tangential sections
section_title
5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
novel
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-05-horizontal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
raw_fields
{
  "n": 12,
  "doi": "10.3389/fnana.2024.1364675",
  "claim": "Long-range horizontal axonal projections in Layer 1 of mouse V1 terminate preferentially in M2 muscarinic acetylcholine receptor-negative interpatches, with significantly higher density than in M2+ patches.",
  "cite_key": "Burkhalter2024",
  "evidence": "Anterograde AAV injections were made into mouse V1, axonal projection density was quantified in ROIs divided into M2 intensity quantiles, and Kolmogorov–Smirnov statistics were used to compare projections in M2+ patches versus M2− interpatches.",
  "effect_size": "L1 horizontal projections to M2− interpatches significantly denser than to M2+ patches (KS test p = 5.7e-04, n = 12 ROIs)",
  "text_access": "fulltext",
  "study_system": "mouse V1, anterograde AAV tracing, tangential sections",
  "argument_role": "supporting",
  "replication_status": "novel",
  "claim_source_sentence": "We found that in L1 projections, contained in sections 1 and 2, to M2− interpatches were significantly (= 5.7e-04;= 12) denser than to M2+ patches ().",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "We found that in L1 projections, contained in sections 1 and 2, to M2− interpatches were significantly (= 5.7e-04;= 12) denser than to M2+ patches ()."
}
source_refs
[
  "paper:paper-236876dbc518"
]
evidence_refs
[
  {
    "ref": "paper:paper-236876dbc518"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}
evidence_summary
Anterograde AAV injections were made into mouse V1, axonal projection density was quantified in ROIs divided into M2 intensity quantiles, and Kolmogorov–Smirnov statistics were used to compare projections in M2+ patches versus M2− interpatches.

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