Details

scope
mouse visual cortex, in vitro paired recordings
section_id
section_07_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
effect_size
Qualitative connectivity scheme across three interneuron populations
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
mouse visual cortex, in vitro paired recordings
section_title
Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
evidence_summary
Paired recordings in mouse visual cortex measuring connectivity between molecularly defined interneuron populations across supra- and infra-granular layers
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (6)
claim_text
PV interneurons strongly inhibit one another but provide little inhibition to SOM or VIP populations, while SOM interneurons avoid inhibiting one another but strongly inhibit all other populations, and VIP interneurons preferentially inhibit SOM interneurons
raw_fields
{
  "n": 0,
  "doi": "10.1038/nn.3446",
  "claim": "PV interneurons strongly inhibit one another but provide little inhibition to SOM or VIP populations, while SOM interneurons avoid inhibiting one another but strongly inhibit all other populations, and VIP interneurons preferentially inhibit SOM interneurons",
  "evidence": "Paired recordings in mouse visual cortex measuring connectivity between molecularly defined interneuron populations across supra- and infra-granular layers",
  "effect_size": "Qualitative connectivity scheme across three interneuron populations",
  "text_access": "fulltext",
  "study_system": "mouse visual cortex, in vitro paired recordings",
  "replication_status": "independently replicated",
  "claim_source_sentence": "Parvalbumin expressing interneurons strongly inhibit one another but, surprisingly, provide little inhibition to other populations. In contrast, somatostatin expressing interneurons avoid inhibiting one another, yet strongly inhibit all other populations. Finally, vasoactive intestinal peptide expressing interneurons preferentially inhibit somatostatin interneurons.",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2016.06.033"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-1659c2dc5d60"
]
source_span
Parvalbumin expressing interneurons strongly inhibit one another but, surprisingly, provide little inhibition to other populations. In contrast, somatostatin expressing interneurons avoid inhibiting one another, yet strongly inhibit all other populations. Finally, vasoactive intestinal peptide expressing interneurons preferentially inhibit somatostatin interneurons.
evidence_refs
[
  {
    "ref": "paper:paper-1659c2dc5d60"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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