- raw_fields
{
"n": 0,
"doi": "10.3390/cells14050321",
"claim": "Perineuronal nets predominantly surround inhibitory neurons and regulate synaptic plasticity and neuronal excitability in the CNS",
"evidence": "Review summarizing PNN molecular composition, structure, functional roles, and involvement in neurological diseases",
"effect_size": null,
"text_access": "fulltext",
"study_system": "review, multiple species",
"replication_status": "independently_replicated",
"claim_source_sentence": "Perineuronal nets (PNNs) are specialized extracellular matrix structures that predominantly surround inhibitory neurons in the central nervous system (CNS). They have been identified as crucial regulators of synaptic plasticity and neuronal excitability.",
"replication_evidence_dois": [
"10.18240/ijo.2025.12.03"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-677a9bb28a83"
]
- source_span
Perineuronal nets (PNNs) are specialized extracellular matrix structures that predominantly surround inhibitory neurons in the central nervous system (CNS). They have been identified as crucial regulators of synaptic plasticity and neuronal excitability.
- evidence_refs
[
{
"ref": "paper:paper-677a9bb28a83"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}