Cortical interneuron diversity is regulated by genetic programs initiated in MG…

Details

scope: mouse, review
claim_text: Cortical interneuron diversity is regulated by genetic programs initiated in MGE progenitors, with temporal and spatial patterning within the MGE contributing to subtype specification
section_id: section_03_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_03_evidence_package.json
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-03
source_kind: review_finding
source_path: evidence/section_03_evidence_package.json
source_span: Genetic programs controlling cortical interneuron fate
study_system: mouse, review
section_title: Developmental Origins: MGE Lineage, Specification, and Migration
evidence_summary: Review synthesizing evidence that transcription factor cascades initiated by Nkx2-1 in MGE progenitors lead to PV and SST specification via Lhx6 and downstream factors
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: independently_replicated
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-03
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_03_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1016/j.conb.2013.12.012",
  "claim": "Cortical interneuron diversity is regulated by genetic programs initiated in MGE progenitors, with temporal and spatial patterning within the MGE contributing to subtype specification",
  "evidence": "Review synthesizing evidence that transcription factor cascades initiated by Nkx2-1 in MGE progenitors lead to PV and SST specification via Lhx6 and downstream factors",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse, review",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Genetic programs controlling cortical interneuron fate",
  "replication_evidence_dois": [
    "10.1242/dev.015123",
    "10.1016/j.neuron.2014.02.030"
  ],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-5f47072d0435"
]

evidence_refs

[
  {
    "ref": "paper:paper-5f47072d0435"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Cortical interneuron diversity is regulated by genetic programs initiated in MG…

Details

Replication

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