Details

scope
mouse neocortex layer 6, in vitro
claim_text
PV inhibitory neurons in a L6 sublamina send axons through cortical layers toward the pia, generating interlaminar inhibitory output, and receive stronger thalamocortical input than neighboring pyramidal neurons
section_id
section_07_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
effect_size
L6 PV neurons receive stronger TC input than L6 pyramidal cells
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
mouse neocortex layer 6, in vitro
section_title
Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
evidence_summary
In vitro electrophysiology and anatomical tracing in mouse cortex L6
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
single study
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.celrep.2019.08.048",
  "claim": "PV inhibitory neurons in a L6 sublamina send axons through cortical layers toward the pia, generating interlaminar inhibitory output, and receive stronger thalamocortical input than neighboring pyramidal neurons",
  "evidence": "In vitro electrophysiology and anatomical tracing in mouse cortex L6",
  "effect_size": "L6 PV neurons receive stronger TC input than L6 pyramidal cells",
  "text_access": "fulltext",
  "study_system": "mouse neocortex layer 6, in vitro",
  "replication_status": "single study",
  "claim_source_sentence": "The vast majority of parvalbumin inhibitory neurons in a sublamina within L6 send axons through the cortical layers toward the pia. These interlaminar inhibitory neurons receive local synaptic inputs from both major types of L6 excitatory neurons and receive stronger input from thalamocortical afferents than do neighboring pyramidal neurons.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "These interlaminar inhibitory neurons receive stronger input from thalamocortical afferents than do neighboring pyramidal neurons."
}
source_refs
[
  "paper:paper-ab9407c26ea7"
]
source_span
The vast majority of parvalbumin inhibitory neurons in a sublamina within L6 send axons through the cortical layers toward the pia. These interlaminar inhibitory neurons receive local synaptic inputs from both major types of L6 excitatory neurons and receive stronger input from thalamocortical afferents than do neighboring pyramidal neurons.
evidence_refs
[
  {
    "ref": "paper:paper-ab9407c26ea7"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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