Details
- scope
- mouse, review of transplantation studies
- claim_text
- Transplanted MGE cells migrate to different brain regions, differentiate into multiple GABAergic interneuron subtypes, and enhance synaptic inhibition with therapeutic potential for interneuron disorders
- section_id
- section_03_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_03_evidence_package.json
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-03
- source_kind
- review_finding
- source_path
- evidence/section_03_evidence_package.json
- source_span
- After transplantation, MGE cells migrate to different brain regions, differentiate into multiple subtypes of GABAergic interneurons, integrate into host neural circuits, enhance synaptic inhibition
- study_system
- mouse, review of transplantation studies
- section_title
- Developmental Origins: MGE Lineage, Specification, and Migration
- evidence_summary
- Review of MGE transplantation for epilepsy, schizophrenia, ASD, and Alzheimer's disease
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-03
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_03_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.3389/fncel.2022.939294", "claim": "Transplanted MGE cells migrate to different brain regions, differentiate into multiple GABAergic interneuron subtypes, and enhance synaptic inhibition with therapeutic potential for interneuron disorders", "evidence": "Review of MGE transplantation for epilepsy, schizophrenia, ASD, and Alzheimer's disease", "effect_size": null, "text_access": "fulltext", "study_system": "mouse, review of transplantation studies", "replication_status": "independently_replicated", "claim_source_sentence": "After transplantation, MGE cells migrate to different brain regions, differentiate into multiple subtypes of GABAergic interneurons, integrate into host neural circuits, enhance synaptic inhibition", "replication_evidence_dois": [ "10.1073/pnas.1316488111", "10.1016/j.stem.2023.08.013" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-87df39a05d7f" ]
- evidence_refs
[ { "ref": "paper:paper-87df39a05d7f" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }