Details

scope
mouse primary auditory cortex (single male)
claim_text
Axonal BARseq mapped long-range projections of >8,000 single primary auditory cortex neurons from a single mouse and quantitatively revealed that individual mouse IT neurons project to different cortical layers in an area-dependent manner.
section_id
section_07
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
effect_size
>8,000 single neurons in a single mouse
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-07-celltype-motifs
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
source_span
As a proof of principle, we have mapped the long-range projections of >8000 primary auditory cortex neurons from a single male mouse.
study_system
mouse primary auditory cortex (single male)
section_title
7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity
evidence_summary
In situ sequencing of RNA barcodes (axonal BARseq) to read out projection targets and axonal trajectories of densely labeled cortical neurons in mouse.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
within_lab_replicated
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-07-celltype-motifs
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": 8000,
  "doi": "10.1038/s41467-024-52756-x",
  "claim": "Axonal BARseq mapped long-range projections of >8,000 single primary auditory cortex neurons from a single mouse and quantitatively revealed that individual mouse IT neurons project to different cortical layers in an area-dependent manner.",
  "cite_key": "Yuan2024b",
  "evidence": "In situ sequencing of RNA barcodes (axonal BARseq) to read out projection targets and axonal trajectories of densely labeled cortical neurons in mouse.",
  "effect_size": ">8,000 single neurons in a single mouse",
  "text_access": "abstract_only",
  "study_system": "mouse primary auditory cortex (single male)",
  "argument_role": "supporting",
  "replication_status": "within_lab_replicated",
  "claim_source_sentence": "As a proof of principle, we have mapped the long-range projections of >8000 primary auditory cortex neurons from a single male mouse.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1016/j.cell.2019.09.023"
  ],
  "effect_size_source_sentence": "The large sample size enabled us to systematically quantify the projections of intratelencephalic (IT) neurons, and revealed that individual IT neurons project to different layers in an area-dependent fashion."
}
source_refs
[
  "paper:paper-986527ad59ef"
]
evidence_refs
[
  {
    "ref": "paper:paper-986527ad59ef"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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