In mouse cortex, paired patch recordings from retrogradely labeled corticostria…

In mouse cortex, paired patch recordings from retrogradely labeled corticostriatal, corticocortical and corticotectal pyramidal neurons showed that connection probability depends on both presynaptic and postsynaptic projection identity, with feed-forward connections from corticocortical to corticotectal neurons ~3–4 fold higher than monosynaptic connections among corticocortical or corticotectal cells.

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  "doi": "10.1038/nature07658",
  "claim": "In mouse cortex, paired patch recordings from retrogradely labeled corticostriatal, corticocortical and corticotectal pyramidal neurons showed that connection probability depends on both presynaptic and postsynaptic projection identity, with feed-forward connections from corticocortical to corticotectal neurons ~3–4 fold higher than monosynaptic connections among corticocortical or corticotectal cells.",
  "cite_key": "Brown2009",
  "evidence": "Up to four-cell simultaneous whole-cell recordings of retrogradely labeled mouse pyramidal neurons.",
  "effect_size": "≈3- to 4-fold higher feed-forward connection probability corticocortical→corticotectal vs corticocortical↔corticocortical or corticotectal↔corticotectal",
  "text_access": "abstract_only",
  "study_system": "mouse cortex (V1/auditory), retrogradely labeled corticostriatal, corticocortical, corticotectal pyramidal neurons",
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  "claim_source_sentence": "We then show that the probability of feed-forward connections from corticocortical neurons to corticotectal neurons is approximately three- to fourfold higher than the probability of monosynaptic connections among corticocortical or corticotectal cells.",
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    "10.1523/JNEUROSCI.0772-11.2011",
    "10.1523/JNEUROSCI.2810-11.2012"
  ],
  "effect_size_source_sentence": "We then show that the probability of feed-forward connections from corticocortical neurons to corticotectal neurons is approximately three- to fourfold higher than the probability of monosynaptic connections among corticocortical or corticotectal cells."
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]

We then show that the probability of feed-forward connections from corticocortical neurons to corticotectal neurons is approximately three- to fourfold higher than the probability of monosynaptic connections among corticocortical or corticotectal cells.

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