- claim_text
Single-neuron whole-brain reconstruction of 1,023 mouse pyramidal neurons from Cre-driver-line-defined IT and PT classes across six sensorimotor subregions reveals projection-subtype mosaics with hierarchical and laminar diversity in axonal patterns.
- raw_fields
{
"n": 1023,
"doi": "10.34133/research.0470",
"claim": "Single-neuron whole-brain reconstruction of 1,023 mouse pyramidal neurons from Cre-driver-line-defined IT and PT classes across six sensorimotor subregions reveals projection-subtype mosaics with hierarchical and laminar diversity in axonal patterns.",
"cite_key": "Yao2024",
"evidence": "High-resolution whole-brain imaging and single-neuron axon/dendrite reconstruction of Cre-line-labeled mouse pyramidal neurons.",
"effect_size": "1,023 reconstructed neurons across 6 subregions",
"text_access": "abstract_only",
"study_system": "mouse sensorimotor cortex, IT and PT Cre-driver lines",
"argument_role": "supporting",
"replication_status": "independently_replicated",
"claim_source_sentence": "Here, using mouse Cre driver lines and high-resolution whole-brain imaging to selectively trace the axons and dendrites of cortical pyramidal tract (PT) and intratelencephalic (IT) neurons, we reconstructed the complete morphology of 1,023 pyramidal neurons and generated a projectome of 6 subregions within the sensorimotor cortex.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [
"10.1016/j.isci.2023.106316",
"10.7554/eLife.97602"
],
"effect_size_source_sentence": "…we reconstructed the complete morphology of 1,023 pyramidal neurons and generated a projectome of 6 subregions within the sensorimotor cortex."
}- source_refs
[
"paper:paper-2e5a1035a887"
]
- source_span
Here, using mouse Cre driver lines and high-resolution whole-brain imaging to selectively trace the axons and dendrites of cortical pyramidal tract (PT) and intratelencephalic (IT) neurons, we reconstructed the complete morphology of 1,023 pyramidal neurons and generated a projectome of 6 subregions within the sensorimotor cortex.
- evidence_refs
[
{
"ref": "paper:paper-2e5a1035a887"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}