Details
- scope
- mouse cortex and thalamus, Cre-driver lines
- section_id
- section_07
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
- effect_size
- ~1,000 tracer experiments; shallow hierarchy of cell-class-specific connections
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-07-celltype-motifs
- source_kind
- review_finding
- source_path
- evidence/section_07_evidence_package.json
- source_span
- We used Cre driver lines (mice expressing Cre recombinase) to comprehensively and selectively label brain-wide connections by layer and class of projection neuron.
- study_system
- mouse cortex and thalamus, Cre-driver lines
- section_title
- 7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity
- evidence_summary
- ~1,000 new viral tracer experiments across cortex and thalamus in Cre-driver mouse lines, integrated into the Allen Mouse Brain Connectivity Atlas.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-07-celltype-motifs
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- claim_text
Cre-driver-line tracing of ~1,000 cortical and thalamic projection experiments derived generalized anatomical rules for cortico-cortical, thalamocortical and corticothalamic projections and built a feedforward/feedback hierarchical model with cell-class-specific connections occupying a shallow hierarchy in the mouse cortex.
- raw_fields
{ "n": 1000, "doi": "10.1038/s41586-019-1716-z", "claim": "Cre-driver-line tracing of ~1,000 cortical and thalamic projection experiments derived generalized anatomical rules for cortico-cortical, thalamocortical and corticothalamic projections and built a feedforward/feedback hierarchical model with cell-class-specific connections occupying a shallow hierarchy in the mouse cortex.", "cite_key": "Harris2019", "evidence": "~1,000 new viral tracer experiments across cortex and thalamus in Cre-driver mouse lines, integrated into the Allen Mouse Brain Connectivity Atlas.", "effect_size": "~1,000 tracer experiments; shallow hierarchy of cell-class-specific connections", "text_access": "abstract_only", "study_system": "mouse cortex and thalamus, Cre-driver lines", "argument_role": "supporting", "replication_status": "independently_replicated", "claim_source_sentence": "We used Cre driver lines (mice expressing Cre recombinase) to comprehensively and selectively label brain-wide connections by layer and class of projection neuron.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [ "10.7554/eLife.97602", "10.1016/j.isci.2023.106316" ], "effect_size_source_sentence": "Our results show that cell-class-specific connections are organized in a shallow hierarchy within the mo" }- source_refs
[ "paper:paper-259a50694faa" ]
- evidence_refs
[ { "ref": "paper:paper-259a50694faa" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }