- claim_text
In mouse barrel S1, long-range M1→S1 synapses contact L5 IT and L5 PT neurons with opposite short-term dynamics — depression at IT targets and facilitation at PT targets — yielding two functionally distinct parallel corticocortical excitatory pathways.
- raw_fields
{
"n": 0,
"doi": "10.1523/eneuro.0154-24.2024",
"claim": "In mouse barrel S1, long-range M1→S1 synapses contact L5 IT and L5 PT neurons with opposite short-term dynamics — depression at IT targets and facilitation at PT targets — yielding two functionally distinct parallel corticocortical excitatory pathways.",
"cite_key": "Kim2024b",
"evidence": "Optogenetic activation of M1 terminals combined with whole-cell recordings of retrogradely labeled L5 IT and PT neurons in S1 of male and female mice.",
"effect_size": "qualitative — depression at IT vs facilitation at PT; larger PT amplitudes during trains",
"text_access": "abstract_only",
"study_system": "mouse barrel S1, L5 IT and PT neurons",
"argument_role": "supporting",
"replication_status": "replication_unknown",
"claim_source_sentence": "We found that M1 synapses onto IT cells displayed modest short-term depression, whereas synapses onto PT neurons showed robust short-term facilitation.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": "…resulting in larger response amplitudes in PT neurons than IT cells during repetitive stimulation."
}- source_refs
[
"paper:paper-4f08ea59de5f"
]
- evidence_refs
[
{
"ref": "paper:paper-4f08ea59de5f"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}