Details

scope
mouse forelimb M1 and M2 (caudal and rostral forelimb areas)
section_id
section_07
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
effect_size
four PT axon subclasses (M1-CSPI, M1-CBULB, M2-CSPI, M2-CBULB)
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-07-celltype-motifs
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
source_span
The four basic axon subclasses comprising these projections (M1-CSPI, M1-CBULB, M2-CSPI, M2-CBULB) showed a complex mix of differences and similarities in their brainstem projection profiles.
study_system
mouse forelimb M1 and M2 (caudal and rostral forelimb areas)
section_title
7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity
evidence_summary
MAPseq single-axon-resolution molecular barcoding of M1 and M2 PT axons in male and female mice.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-07-celltype-motifs
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
Multiplexed MAPseq molecular barcoding revealed that mouse forelimb M1 and M2 pyramidal-tract axons partition into corticospinal and corticobulbar subclasses with overlapping but distinguishable brainstem branching profiles, with graded clustering of subclass composition rather than discrete projection types.
raw_fields
{
  "n": 0,
  "doi": "10.1523/jneurosci.1062-22.2022",
  "claim": "Multiplexed MAPseq molecular barcoding revealed that mouse forelimb M1 and M2 pyramidal-tract axons partition into corticospinal and corticobulbar subclasses with overlapping but distinguishable brainstem branching profiles, with graded clustering of subclass composition rather than discrete projection types.",
  "cite_key": "Hausmann2022",
  "evidence": "MAPseq single-axon-resolution molecular barcoding of M1 and M2 PT axons in male and female mice.",
  "effect_size": "four PT axon subclasses (M1-CSPI, M1-CBULB, M2-CSPI, M2-CBULB)",
  "text_access": "abstract_only",
  "study_system": "mouse forelimb M1 and M2 (caudal and rostral forelimb areas)",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "The four basic axon subclasses comprising these projections (M1-CSPI, M1-CBULB, M2-CSPI, M2-CBULB) showed a complex mix of differences and similarities in their brainstem projection profiles.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/s41586-018-0642-9",
    "10.1016/j.cell.2019.09.023"
  ],
  "effect_size_source_sentence": "Cluster analysis showed graded distributions of the basic subclasses within the PT class."
}
source_refs
[
  "paper:paper-9c44f8966e47"
]
evidence_refs
[
  {
    "ref": "paper:paper-9c44f8966e47"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.