In rat frontal cortex L5 callosal (commissural) projection neurons subdivide by…

In rat frontal cortex L5 callosal (commissural) projection neurons subdivide by firing pattern; same-firing-pattern COM cell pairs are connected more often, and L2/3 COM cells preferentially innervate L5 COM cells, organizing the commissural system into hierarchically nested projection-specific subnetworks.

{
  "n": 0,
  "doi": "10.1523/jneurosci.5795-10.2011",
  "claim": "In rat frontal cortex L5 callosal (commissural) projection neurons subdivide by firing pattern; same-firing-pattern COM cell pairs are connected more often, and L2/3 COM cells preferentially innervate L5 COM cells, organizing the commissural system into hierarchically nested projection-specific subnetworks.",
  "cite_key": "Otsuka2011",
  "evidence": "Whole-cell recordings from retrogradely labeled rat frontal cortex callosal projection neurons.",
  "effect_size": "qualitative — connection probability higher within firing subtype than between",
  "text_access": "abstract_only",
  "study_system": "rat frontal cortex L2/3 and L5 callosal projection neurons",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "The probability of synaptically connected pairs of L5 COM cells was higher in cell pairs of the same firing subtypes than that in different cell subtype pairs.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1093/cercor/bhaa297",
    "10.1523/JNEUROSCI.0772-11.2011"
  ],
  "effect_size_source_sentence": "The probability of synaptically connected pairs of L5 COM cells was higher in cell pairs of the same firing subtypes than that in different cell subtype pairs."
}

[
  "paper:paper-c0dd41d028b4"
]

[
  {
    "ref": "paper:paper-c0dd41d028b4"
  }
]

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}