Details
- scope
- mouse dorsal striatum, PV-Cre, D1-Cre, D2-Cre
- claim_text
- Optogenetic stimulation of whisker S1-corticostriatal axons preferentially recruits striatal PV interneurons and produces task-specific behavioral inhibition, whereas M1-corticostriatal stimulation produces opposite behavioral effects.
- section_id
- section_11
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-11
- source_kind
- review_finding
- source_path
- evidence/section_11_evidence_package.json
- study_system
- mouse dorsal striatum, PV-Cre, D1-Cre, D2-Cre
- section_title
- Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)
- evidence_summary
- Cell-type-targeted optogenetics in PV-Cre, D1-Cre, D2-Cre mice with sensory-guided behavior.
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-11
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
- raw_fields
{ "n": 0, "doi": "10.1016/j.cub.2019.03.028", "claim": "Optogenetic stimulation of whisker S1-corticostriatal axons preferentially recruits striatal PV interneurons and produces task-specific behavioral inhibition, whereas M1-corticostriatal stimulation produces opposite behavioral effects.", "cite_key": "Lee2019b", "evidence": "Cell-type-targeted optogenetics in PV-Cre, D1-Cre, D2-Cre mice with sensory-guided behavior.", "effect_size": null, "text_access": "abstract_only", "study_system": "mouse dorsal striatum, PV-Cre, D1-Cre, D2-Cre", "source_cluster_id": "cluster_10", "replication_status": "replication_unknown", "claim_source_sentence": "Optogenetic stimulation of S1-corticostriatal afferents in ex vivo recordings produced larger postsynaptic potentials in striatal parvalbumin (PV)-expressing interneurons than D1- or D2-expressing spiny projection neurons (SPNs), an effect not observed for M1-corticostriatal afferents.", "replication_evidence_dois": [], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-c90ee9c44468" ]
- source_span
Optogenetic stimulation of S1-corticostriatal afferents in ex vivo recordings produced larger postsynaptic potentials in striatal parvalbumin (PV)-expressing interneurons than D1- or D2-expressing spiny projection neurons (SPNs), an effect not observed for M1-corticostriatal afferents.
- evidence_refs
[ { "ref": "paper:paper-c90ee9c44468" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }