Details

scope
basal ganglia network model (rodent-constrained)
section_id
section_11
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
effect_size
few percent of direct pathway MSNs sufficient for full SNr inhibition
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-11
source_kind
review_finding
source_path
evidence/section_11_evidence_package.json
source_span
In particular, our simulations indicate that bursting in only a few percent of the direct pathway MSNs is sufficient for completely inhibiting SNr neuron activity.
study_system
basal ganglia network model (rodent-constrained)
section_title
Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)
evidence_summary
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-11
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
claim_text
A constrained network model of basal ganglia output predicts that bursting in only a few percent of direct- or indirect-pathway MSNs can fully inhibit or excite SNr activity, with SNr dynamics dominated by direct GPe-SNr projections rather than the disinhibitory indirect-pathway scheme.
raw_fields
{
  "n": 0,
  "doi": "10.3389/fncom.2013.00076",
  "claim": "A constrained network model of basal ganglia output predicts that bursting in only a few percent of direct- or indirect-pathway MSNs can fully inhibit or excite SNr activity, with SNr dynamics dominated by direct GPe-SNr projections rather than the disinhibitory indirect-pathway scheme.",
  "cite_key": "Lindahl2013",
  "evidence": "",
  "effect_size": "few percent of direct pathway MSNs sufficient for full SNr inhibition",
  "text_access": "fulltext",
  "study_system": "basal ganglia network model (rodent-constrained)",
  "source_cluster_id": "cluster_10",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "In particular, our simulations indicate that bursting in only a few percent of the direct pathway MSNs is sufficient for completely inhibiting SNr neuron activity.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "In particular, our simulations indicate that bursting in only a few percent of the direct pathway MSNs is sufficient for completely inhibiting SNr neuron activity."
}
source_refs
[
  "paper:paper-bd764907c827"
]
evidence_refs
[
  {
    "ref": "paper:paper-bd764907c827"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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