- raw_fields
{
"n": 8,
"doi": "10.1523/jneurosci.1473-24.2024",
"claim": "A chimeric light-activated DRD2 (OptoDRD2) expressed in glutamatergic neurons of the lateral globus pallidus drives DRD2-like Gαi/o signaling and increases locomotion in male mice.",
"cite_key": "Kim2024b",
"evidence": "Cell-based cAMP/ERK assays + AAV expression in LGP excitatory neurons + open-field behavior.",
"effect_size": "2",
"text_access": "fulltext",
"study_system": "male mouse, lateral globus pallidus",
"source_cluster_id": "cluster_10",
"replication_status": "replication_unknown",
"claim_source_sentence": "The optogenetic stimulation of OptoDRD2 in the LGP region affected a wide range of locomotion-related parameters, such as increased frequency of movement and decreased immobility time, resulting in the facilitation of motor function of living male mice.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "The optogenetic stimulation of OptoDRD2 in the LGP region affected a wide range of locomotion-related parameters, such as increased frequency of movement and decreased immobility time, resulting in the facilitation of motor function of living male mice."
}- source_refs
[
"paper:paper-620809df3687"
]
- source_span
The optogenetic stimulation of OptoDRD2 in the LGP region affected a wide range of locomotion-related parameters, such as increased frequency of movement and decreased immobility time, resulting in the facilitation of motor function of living male mice.
- evidence_refs
[
{
"ref": "paper:paper-620809df3687"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}