Details

scope
computational model with mouse V1 empirical-data validation
section_id
section_07
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
effect_size
qualitative — temporal-prediction objective recapitulates multiple empirical V1 wiring biases
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-07-celltype-motifs
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
computational model with mouse V1 empirical-data validation
section_title
7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity
evidence_summary
Training RNNs on a temporal-prediction objective with natural visual movies and comparing emergent connectivity statistics to published mouse-V1 paired-recording datasets.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single_study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-07-celltype-motifs
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (6)
claim_text
A recurrent neural network optimized to predict upcoming sensory inputs from natural visual stimuli spontaneously develops the functional-connectivity rules observed empirically in mouse V1, including like-to-like excitatory connectivity, the relationship between connectivity and orientation/direction tuning, and the response-similarity gradient with connection strength — suggesting that temporal prediction may be an underlying organizational principle of V1 lateral connectivity.
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.cub.2024.11.073",
  "claim": "A recurrent neural network optimized to predict upcoming sensory inputs from natural visual stimuli spontaneously develops the functional-connectivity rules observed empirically in mouse V1, including like-to-like excitatory connectivity, the relationship between connectivity and orientation/direction tuning, and the response-similarity gradient with connection strength — suggesting that temporal prediction may be an underlying organizational principle of V1 lateral connectivity.",
  "cite_key": "KlavinskisWhiting2025",
  "evidence": "Training RNNs on a temporal-prediction objective with natural visual movies and comparing emergent connectivity statistics to published mouse-V1 paired-recording datasets.",
  "effect_size": "qualitative — temporal-prediction objective recapitulates multiple empirical V1 wiring biases",
  "text_access": "fulltext",
  "study_system": "computational model with mouse V1 empirical-data validation",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "the functional specificity of V1 connections emerges naturally in a recurrent neural network optimized to predict upcoming sensory inputs for natural visual stimuli. This temporal prediction model reproduces the complex relationships between the connectivity of V1 neurons and their orientation and direction preferences",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "the functional specificity of V1 connections emerges naturally in a recurrent neural network optimized to predict upcoming sensory inputs for natural visual stimuli"
}
source_refs
[
  "paper:paper-d66965754b34"
]
source_span
the functional specificity of V1 connections emerges naturally in a recurrent neural network optimized to predict upcoming sensory inputs for natural visual stimuli. This temporal prediction model reproduces the complex relationships between the connectivity of V1 neurons and their orientation and direction preferences
evidence_refs
[
  {
    "ref": "paper:paper-d66965754b34"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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