Feature-specific excitatory connectivity in mouse V1 L2/3 emerges over the seco…

Feature-specific excitatory connectivity in mouse V1 L2/3 emerges over the second-to-third postnatal week and requires visual experience, with juvenile-stage like-to-like connectivity being initially absent but established by experience-dependent refinement.

{
  "n": 0,
  "doi": "10.1523/jneurosci.0875-14.2014",
  "claim": "Feature-specific excitatory connectivity in mouse V1 L2/3 emerges over the second-to-third postnatal week and requires visual experience, with juvenile-stage like-to-like connectivity being initially absent but established by experience-dependent refinement.",
  "cite_key": "Ko2014",
  "evidence": "In-vivo two-photon imaging of visual responses followed by multi-cell paired recordings in mouse V1 L2/3 across postnatal development, in normal and dark-reared mice.",
  "effect_size": "qualitative — feature-specific E→E connectivity is a postnatally established (and partly experience-dependent) property",
  "text_access": "abstract_only",
  "study_system": "mouse primary visual cortex L2/3, postnatal development and dark-rearing",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Emergence of Feature-Specific Connectivity in Cortical Microcircuits in the Absence of Visual Experience",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/nature11526",
    "10.1038/nature14182"
  ],
  "effect_size_source_sentence": "Emergence of Feature-Specific Connectivity in Cortical Microcircuits"
}

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