- claim_text
Mouse V1 PV+ inhibitory interneurons connect densely but with tuned synaptic weights: individual PV+ cells most strongly inhibit those pyramidal cells that provide them with the strongest excitation and share their visual selectivity, producing feature-specific recurrent inhibition that stabilizes activity within excitatory feature ensembles.
- raw_fields
{
"n": 0,
"doi": "10.1016/j.neuron.2023.12.013",
"claim": "Mouse V1 PV+ inhibitory interneurons connect densely but with tuned synaptic weights: individual PV+ cells most strongly inhibit those pyramidal cells that provide them with the strongest excitation and share their visual selectivity, producing feature-specific recurrent inhibition that stabilizes activity within excitatory feature ensembles.",
"cite_key": "Znamenskiy2024",
"evidence": "Two-photon imaging of visual responses combined with paired patch-clamp recording of PV+ and pyramidal cells in mouse V1.",
"effect_size": "qualitative — co-tuned PV→pyramidal weight specificity overlaying dense connectivity",
"text_access": "fulltext",
"study_system": "mouse primary visual cortex (V1) PV+ interneurons and pyramidal neurons",
"argument_role": "supporting",
"replication_status": "independently_replicated",
"claim_source_sentence": "Individual PV+ cells strongly inhibit those pyramidal cells that provide them with strong excitation and share their visual selectivity",
"source_provenance_status": "ok",
"replication_evidence_dois": [
"10.1038/nature14182"
],
"effect_size_source_sentence": "the synaptic weights of their connections to nearby pyramidal neurons are specifically tuned according to the similarity of the cells' responses"
}- source_refs
[
"paper:paper-7ab8027f125a"
]
- evidence_refs
[
{
"ref": "paper:paper-7ab8027f125a"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}