Details

scope
rat hippocampus, light + electron microscopy
section_id
section_10
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json
effect_size
2-5 contacts per axon; 2-10 CR-IR axons converge onto single CR cell; up to 15 cells per cluster
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-10-oscillatory-dynamics
source_kind
review_finding
source_path
evidence/section_10_evidence_package.json
study_system
rat hippocampus, light + electron microscopy
section_title
Oscillatory Dynamics and Temporal Coordination
evidence_summary
3D reconstruction, electron microscopy, and postembedding immunogold staining for GABA in rat hippocampus.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-10-oscillatory-dynamics
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
claim_text
Hippocampal calretinin-immunoreactive interneurons form interconnected dendro-dendritic clusters and selectively innervate GABAergic targets including VIP-containing basket cells, providing the anatomical substrate for VIP-IS interneuron-specific disinhibition that paces other interneurons during oscillations.
raw_fields
{
  "n": null,
  "doi": "10.1523/jneurosci.16-10-03397.1996",
  "pmid": "",
  "year": 1996,
  "claim": "Hippocampal calretinin-immunoreactive interneurons form interconnected dendro-dendritic clusters and selectively innervate GABAergic targets including VIP-containing basket cells, providing the anatomical substrate for VIP-IS interneuron-specific disinhibition that paces other interneurons during oscillations.",
  "pmcid": "",
  "title": "Interneurons Containing Calretinin Are Specialized to Control Other Interneurons in the Rat Hippocampus",
  "authors": "",
  "journal": "",
  "cite_key": "Gulyas1996",
  "evidence": "3D reconstruction, electron microscopy, and postembedding immunogold staining for GABA in rat hippocampus.",
  "cluster_id": "cluster_09_oscillations",
  "effect_size": "2-5 contacts per axon; 2-10 CR-IR axons converge onto single CR cell; up to 15 cells per cluster",
  "figure_data": [],
  "text_access": "abstract_only",
  "study_system": "rat hippocampus, light + electron microscopy",
  "cited_by_count": 505,
  "_source_cluster": "cluster_09_oscillations",
  "replication_status": "independently_replicated",
  "_source_cluster_index": 26,
  "claim_source_sentence": "CR-containing GABA-immunoreactive axons of local origin formed multiple symmetrical synaptic contacts (two to five) exclusively on GABAergic dendrites (CR-negative as well as CR-positive). Two to 10 CR-IR axons may converge onto a single CR-IR neuron",
  "replication_evidence_dois": [
    "10.1523/jneurosci.3813-13.2014",
    "10.3389/fncel.2010.00130"
  ],
  "effect_size_source_sentence": "Reconstruction of the dendritic trees from six consecutive sections demonstrated that at least 15 cells may participate in a dendro-dendritically connected cluster."
}
source_refs
[
  "paper:paper-891e293dffcb"
]
source_span
CR-containing GABA-immunoreactive axons of local origin formed multiple symmetrical synaptic contacts (two to five) exclusively on GABAergic dendrites (CR-negative as well as CR-positive). Two to 10 CR-IR axons may converge onto a single CR-IR neuron
evidence_refs
[
  {
    "ref": "paper:paper-891e293dffcb"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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