A reduced spiking-network model of cortex with E, PV-like (I), SST-like (S), an…

A reduced spiking-network model of cortex with E, PV-like (I), SST-like (S), and VIP populations exhibits multistability between gamma and beta band rhythms; VIP-driven modulation of SST cells controls switching between coexisting oscillatory regimes, formalizing how external/top-down VIP input gates rhythm selection.

{
  "n": null,
  "doi": "10.1101/2025.10.03.680414",
  "pmid": "",
  "year": "2025",
  "claim": "A reduced spiking-network model of cortex with E, PV-like (I), SST-like (S), and VIP populations exhibits multistability between gamma and beta band rhythms; VIP-driven modulation of SST cells controls switching between coexisting oscillatory regimes, formalizing how external/top-down VIP input gates rhythm selection.",
  "pmcid": "",
  "title": "Multi-stable oscillations in cortical networks with two classes of inhibition",
  "authors": "",
  "journal": "",
  "cite_key": "Sarkar2025",
  "evidence": "Spiking network reduced to 9 mean-field ODEs; bifurcation analysis of E-I-S-VIP dynamics.",
  "cluster_id": "cluster_09_oscillations",
  "effect_size": "multiple coexisting rhythms found across parameter space",
  "figure_data": [],
  "text_access": "abstract_only",
  "study_system": "reduced cortical computational model with E-PV-SST-VIP populations",
  "cited_by_count": 1,
  "_source_cluster": "cluster_09_oscillations",
  "replication_status": "independently_replicated",
  "_source_cluster_index": 36,
  "claim_source_sentence": "These S cells are modulated by a third inhibitory subtype, VIP neurons that receive inputs from other cortical areas. Using tools from nonlinear dynamics, we explore the roles of each of the two classes of inhibition as well as the role of the VIP modulation on the properties of these rhythms.",
  "replication_evidence_dois": [
    "10.7554/elife.77594",
    "10.1093/cercor/bhac355"
  ],
  "effect_size_source_sentence": "we find many instances of multiple rhythms within the network."
}

[
  "paper:paper-406a4ca8b0fd"
]

These S cells are modulated by a third inhibitory subtype, VIP neurons that receive inputs from other cortical areas. Using tools from nonlinear dynamics, we explore the roles of each of the two classes of inhibition as well as the role of the VIP modulation on the properties of these rhythms.

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    "Local review repositories are read-only inputs.",
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  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
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