Details

scope
SOM-Cre and PV-Cre mice with optogenetic perturbation in mouse V1
claim_text
Somatostatin-expressing inhibitory neurons (SOMs) in superficial layers of mouse visual cortex are preferentially excited by horizontal cortical axons and causally mediate surround suppression of pyramidal neurons.
section_id
section_11
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-11
source_kind
review_finding
source_path
evidence/section_11_evidence_package.json
source_span
Here we discover that, in contrast to pyramidal cells, the response of somatostatin expressing inhibitory neurons (SOMs) in the superficial layers of the mouse visual cortex increases with stimulation of the receptive field surround.
study_system
SOM-Cre and PV-Cre mice with optogenetic perturbation in mouse V1
section_title
Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)
evidence_summary
Optogenetic silencing of SOM-Cre mice using ChR2/halorhodopsin during in vivo physiology with surround visual stimulation.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-11
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1038/nature11526",
  "claim": "Somatostatin-expressing inhibitory neurons (SOMs) in superficial layers of mouse visual cortex are preferentially excited by horizontal cortical axons and causally mediate surround suppression of pyramidal neurons.",
  "cite_key": "Adesnik2012",
  "evidence": "Optogenetic silencing of SOM-Cre mice using ChR2/halorhodopsin during in vivo physiology with surround visual stimulation.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "SOM-Cre and PV-Cre mice with optogenetic perturbation in mouse V1",
  "source_cluster_id": "cluster_10",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Here we discover that, in contrast to pyramidal cells, the response of somatostatin expressing inhibitory neurons (SOMs) in the superficial layers of the mouse visual cortex increases with stimulation of the receptive field surround.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-48f7973b62f1"
]
evidence_refs
[
  {
    "ref": "paper:paper-48f7973b62f1"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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