Details
- scope
- vip-interneurons
- section_id
- section_10
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json
- effect_size
- VIP/NOS+ interneurons mediated cholinergic-evoked vasodilation; SST cells gave NPY/SST-mediated vasoconstriction.
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-10-oscillatory-dynamics
- source_kind
- review_finding
- source_path
- evidence/section_10_evidence_package.json
- source_span
- The neural circuits recruited by whisker glutamatergic-, basal forebrain cholinergic- or locus coeruleus noradrenergic pathway stimulation were found to be highly specific and discriminative.
- section_title
- Oscillatory Dynamics and Temporal Coordination
- evidence_summary
- Review integrating slice and in vivo work on cortical interneuron + neuromodulatory pathway circuits.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- single_study
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-10-oscillatory-dynamics
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- claim_text
Distinct neuromodulatory pathways (basal forebrain ACh, locus coeruleus NE) recruit highly specific cortical VIP/NOS/CCK interneuron subtypes that mediate region- and state-dependent neurovascular coupling, providing a mechanistic basis by which neuromodulator state alters BOLD signals.
- raw_fields
{ "n": null, "doi": "10.1098/rstb.2015.0350", "year": "2016", "claim": "Distinct neuromodulatory pathways (basal forebrain ACh, locus coeruleus NE) recruit highly specific cortical VIP/NOS/CCK interneuron subtypes that mediate region- and state-dependent neurovascular coupling, providing a mechanistic basis by which neuromodulator state alters BOLD signals.", "title": "Neuronal networks and mediators of cortical neurovascular coupling responses in normal and altered brain states", "journal": "", "species": "multiple", "cite_key": "Lecrux2016", "evidence": "Review integrating slice and in vivo work on cortical interneuron + neuromodulatory pathway circuits.", "effect_size": "VIP/NOS+ interneurons mediated cholinergic-evoked vasodilation; SST cells gave NPY/SST-mediated vasoconstriction.", "text_access": "fulltext", "_source_cluster": "cluster_13_neuromodulation", "replication_status": "single_study", "_source_cluster_index": 32, "claim_source_sentence": "The neural circuits recruited by whisker glutamatergic-, basal forebrain cholinergic- or locus coeruleus noradrenergic pathway stimulation were found to be highly specific and discriminative.", "replication_evidence_dois": [], "effect_size_source_sentence": "Using the whisker-to-barrel pathway as a model of NVC, we can interrogate the reliability of NVC under enhanced cholinergic or noradrenergic modulation of cortical circuits." }- source_refs
[ "paper:paper-fe3c0e54ee6e" ]
- evidence_refs
[ { "ref": "paper:paper-fe3c0e54ee6e" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }