Details

scope
Dystonia patients (focal, multifocal, or generalized) undergoing crossover STN vs GPi DBS
claim_text
In a randomized double-blind crossover trial, 6-month STN-DBS produced larger Burke-Fahn-Marsden movement-score improvement (mean 13.8) than GPi-DBS (mean 9.1) for medically refractory dystonia.
section_id
section_14
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
effect_size
STN 13.8 vs GPi 9.1 BFMDRS points
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-14
source_kind
review_finding
source_path
evidence/section_14_evidence_package.json
source_span
After stimulation of the STN, the mean 6-month improvement in BFMDRS movement score was 13.8 points; after stimulation of the GPi, this improvement was 9.1 points (p = 0.08).
study_system
Dystonia patients (focal, multifocal, or generalized) undergoing crossover STN vs GPi DBS
section_title
Loop Dysfunction in Neurological and Psychiatric Disease
evidence_summary
Prospective double-blind crossover, bilateral electrodes implanted in both STN and GPi of 12 dystonia patients; BFMDRS, SF-36, TWSTRS.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-14
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 12,
  "doi": "10.3171/2013.8.jns13844",
  "claim": "In a randomized double-blind crossover trial, 6-month STN-DBS produced larger Burke-Fahn-Marsden movement-score improvement (mean 13.8) than GPi-DBS (mean 9.1) for medically refractory dystonia.",
  "cite_key": "Schjerling2013",
  "evidence": "Prospective double-blind crossover, bilateral electrodes implanted in both STN and GPi of 12 dystonia patients; BFMDRS, SF-36, TWSTRS.",
  "effect_size": "STN 13.8 vs GPi 9.1 BFMDRS points",
  "text_access": "abstract_only",
  "study_system": "Dystonia patients (focal, multifocal, or generalized) undergoing crossover STN vs GPi DBS",
  "source_cluster_id": "cluster_13",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "After stimulation of the STN, the mean 6-month improvement in BFMDRS movement score was 13.8 points; after stimulation of the GPi, this improvement was 9.1 points (p = 0.08).",
  "replication_evidence_dois": [
    "10.1016/j.xcrm.2026.102783",
    "10.1016/j.xcrm.2026.102711"
  ],
  "effect_size_source_sentence": "After stimulation of the STN, the mean 6-month improvement in BFMDRS movement score was 13.8 points; after stimulation of the GPi, this improvement was 9.1 points (p = 0.08)."
}
source_refs
[
  "paper:paper-2d949c25df58"
]
evidence_refs
[
  {
    "ref": "paper:paper-2d949c25df58"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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