Details

scope
Adults with ADHD (n=20) vs healthy controls (n=20)
claim_text
Adult ADHD shows decreased resting-state functional connectivity between dorsal anterior cingulate and posterior cingulate/precuneus default-mode network components.
section_id
section_14
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
effect_size
DACC–precuneus FC reduction, p<0.0004
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-14
source_kind
review_finding
source_path
evidence/section_14_evidence_package.json
study_system
Adults with ADHD (n=20) vs healthy controls (n=20)
section_title
Loop Dysfunction in Neurological and Psychiatric Disease
evidence_summary
Resting-state 3T fMRI in 20 adults with ADHD and 20 matched controls.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-14
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 20,
  "doi": "10.1016/j.biopsych.2007.06.025",
  "claim": "Adult ADHD shows decreased resting-state functional connectivity between dorsal anterior cingulate and posterior cingulate/precuneus default-mode network components.",
  "cite_key": "Castellanos2008",
  "evidence": "Resting-state 3T fMRI in 20 adults with ADHD and 20 matched controls.",
  "effect_size": "DACC–precuneus FC reduction, p<0.0004",
  "text_access": "fulltext",
  "study_system": "Adults with ADHD (n=20) vs healthy controls (n=20)",
  "source_cluster_id": "cluster_13",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Xavier Castellanos, Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, 14 th Floor, New York, NY 10016, Phone 212-263-3697, Fax 212-263-4675, castef01@nyumc.org Disclosure of Biomedical Financial Interests and Potential Conflicts of Interest: Drs.",
  "replication_evidence_dois": [
    "10.1093/cercor/bhl047",
    "10.1111/j.1460-9568.2010.07110.x"
  ],
  "effect_size_source_sentence": "Group analyses revealed ADHD-related compromises in this relationship, with decreases in the functional connectivity between the anterior cingulate and precuneus/posterior cingulate cortex regions (p < .0004, corrected)."
}
source_refs
[
  "paper:paper-d63aace8c8c9"
]
source_span
Xavier Castellanos, Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, 14 th Floor, New York, NY 10016, Phone 212-263-3697, Fax 212-263-4675, castef01@nyumc.org Disclosure of Biomedical Financial Interests and Potential Conflicts of Interest: Drs.
evidence_refs
[
  {
    "ref": "paper:paper-d63aace8c8c9"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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