Details

scope
Primate models of basal ganglia movement disorders (review)
claim_text
Hypokinetic and hyperkinetic basal ganglia movement disorders (Parkinson's, Huntington's, hemiballism) lie at opposite extremes of a spectrum explained by specific disturbances within the basal ganglia–thalamocortical motor circuit.
section_id
section_14
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-14
source_kind
review_finding
source_path
evidence/section_14_evidence_package.json
source_span
Both extremes of this movement disorder spectrum can be accounted for by postulating specific disturbances within the basal ganglia-thalamocortical 'motor' circuit.
study_system
Primate models of basal ganglia movement disorders (review)
section_title
Loop Dysfunction in Neurological and Psychiatric Disease
evidence_summary
Synthesis of primate model recordings of changes in motor-circuit neuronal activity in hypo- and hyperkinetic basal ganglia disorders.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-14
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1016/0166-2236(90)90110-v",
  "claim": "Hypokinetic and hyperkinetic basal ganglia movement disorders (Parkinson's, Huntington's, hemiballism) lie at opposite extremes of a spectrum explained by specific disturbances within the basal ganglia–thalamocortical motor circuit.",
  "cite_key": "DeLong1990",
  "evidence": "Synthesis of primate model recordings of changes in motor-circuit neuronal activity in hypo- and hyperkinetic basal ganglia disorders.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "Primate models of basal ganglia movement disorders (review)",
  "source_cluster_id": "cluster_13",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Both extremes of this movement disorder spectrum can be accounted for by postulating specific disturbances within the basal ganglia-thalamocortical 'motor' circuit.",
  "replication_evidence_dois": [
    "10.1016/s0090-3019(99)00030-0",
    "10.3233/jpd-130204"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-d7b8b0eb6812"
]
evidence_refs
[
  {
    "ref": "paper:paper-d7b8b0eb6812"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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