Prolonged pallidal beta bursts are a disease-specific feature of OFF-medication…

Details

scope: Pallidal LFP recordings in PD (n=5) and dystonia (n=5) patients
claim_text: Prolonged pallidal beta bursts are a disease-specific feature of OFF-medication Parkinson's disease compared with dystonia or ON-medication PD.
section_id: section_14
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
effect_size: PD-OFF beta-burst duration > PD-ON or dystonia, P<0.05
review_repo: ComputationalReviewLoops
section_ref: wiki_page:computationalreviewloops-14
source_kind: review_finding
source_path: evidence/section_14_evidence_package.json
source_span: Pallidal beta bursts were longer in PD-OFF than PD-ON or dystonia (P < .05).
study_system: Pallidal LFP recordings in PD (n=5) and dystonia (n=5) patients
section_title: Loop Dysfunction in Neurological and Psychiatric Disease
evidence_summary: Pallidal LFP recordings in 5 PD patients ON/OFF and 5 dystonia patients; quantitative burst-duration, amplitude, rate analysis.
review_bundle_ref: analysis_bundle:ab-d49e54403ef9
replication_status: independently_replicated
review_package_ref: analysis_bundle:ab-d49e54403ef9
source_artifact_ref: wiki_page:computationalreviewloops-14
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
commit_sha: 0632aae8abc141909207fe91f6349b9e36489c3b
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops

Raw fields (4)

raw_fields

{
  "n": 10,
  "doi": "10.1002/mds.27524",
  "claim": "Prolonged pallidal beta bursts are a disease-specific feature of OFF-medication Parkinson's disease compared with dystonia or ON-medication PD.",
  "cite_key": "Lofredi2018",
  "evidence": "Pallidal LFP recordings in 5 PD patients ON/OFF and 5 dystonia patients; quantitative burst-duration, amplitude, rate analysis.",
  "effect_size": "PD-OFF beta-burst duration > PD-ON or dystonia, P<0.05",
  "text_access": "abstract_only",
  "study_system": "Pallidal LFP recordings in PD (n=5) and dystonia (n=5) patients",
  "source_cluster_id": "cluster_13",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Pallidal beta bursts were longer in PD-OFF than PD-ON or dystonia (P < .05).",
  "replication_evidence_dois": [
    "10.1063/5.0297677",
    "10.1038/s41598-026-41274-z"
  ],
  "effect_size_source_sentence": "Pallidal beta bursts were longer in PD-OFF than PD-ON or dystonia (P < .05)."
}

source_refs

[
  "paper:paper-e48d65a6df77"
]

evidence_refs

[
  {
    "ref": "paper:paper-e48d65a6df77"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

Prolonged pallidal beta bursts are a disease-specific feature of OFF-medication…

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