Details
- scope
- C57BL/6J knock-in mouse driver and reporter lines, Allen Institute
- section_id
- section_11
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- effect_size
- 23
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-11
- source_kind
- review_finding
- source_path
- evidence/section_11_evidence_package.json
- source_span
- In this paper, we report a large and diverse set of new cell type-specific transgenic mouse lines, including 23 new driver lines (15 Cre and 8 Flp lines) and 26 new reporter lines.
- study_system
- C57BL/6J knock-in mouse driver and reporter lines, Allen Institute
- section_title
- Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)
- evidence_summary
- In situ hybridization, IHC, and electrophysiological characterization across new lines; published Cre/Flp panel.
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- single_study
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-11
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
- claim_text
The Allen Institute TIGRE2.0 transgenic platform yields 23 new Cre/Flp driver lines (15 Cre, 8 Flp) and 26 new Cre-dependent reporter lines targeting cortical and subcortical cell populations, with markedly enhanced single-copy expression and simplified breeding compared to first-generation TIGRE.
- raw_fields
{ "n": 23, "doi": "10.1016/j.cell.2018.06.035", "claim": "The Allen Institute TIGRE2.0 transgenic platform yields 23 new Cre/Flp driver lines (15 Cre, 8 Flp) and 26 new Cre-dependent reporter lines targeting cortical and subcortical cell populations, with markedly enhanced single-copy expression and simplified breeding compared to first-generation TIGRE.", "cite_key": "Daigle2018", "evidence": "In situ hybridization, IHC, and electrophysiological characterization across new lines; published Cre/Flp panel.", "effect_size": "23", "text_access": "fulltext", "study_system": "C57BL/6J knock-in mouse driver and reporter lines, Allen Institute", "source_cluster_id": "cluster_10", "replication_status": "single_study", "claim_source_sentence": "In this paper, we report a large and diverse set of new cell type-specific transgenic mouse lines, including 23 new driver lines (15 Cre and 8 Flp lines) and 26 new reporter lines.", "replication_evidence_dois": [], "effect_size_source_sentence": "In this paper, we report a large and diverse set of new cell type-specific transgenic mouse lines, including 23 new driver lines (15 Cre and 8 Flp lines) and 26 new reporter lines." }- source_refs
[ "paper:paper-c5041cb9303a" ]
- evidence_refs
[ { "ref": "paper:paper-c5041cb9303a" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }