Details
- scope
- mouse S1 L2/3 slice
- section_id
- section_06
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
- effect_size
- Pcon: PV→MC 12/21 (58%), VIP→MC 11/31 (35%); IPSC amplitude PV 456.55±43.22 pA, VIP 275.70±46.59 pA; PV depressing, VIP facilitating at high freq.
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-06-synaptic-properties
- source_kind
- review_finding
- source_path
- evidence/section_06_evidence_package.json
- source_span
- The connection probability was higher for PV cells (∼58%, 12/21) than for VIP cells (∼35%, 11/31) ( ).
- study_system
- mouse S1 L2/3 slice
- section_title
- Synaptic Properties and Connectivity
- evidence_summary
- Optogenetic ChR2 activation + paired whole-cell recordings of PV→MC and VIP→MC pairs in L2/3 S1.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-06-synaptic-properties
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- claim_text
In L2/3 of mouse S1, both PV+ and VIP+ interneurons monosynaptically inhibit Martinotti (SST+) cells but with distinct properties: connection probability ~58% PV→MC vs ~35% VIP→MC; mean IPSC amplitude PV 456.55±43.22 pA vs VIP 275.70±46.59 pA; PV→MC inputs depress while VIP→MC inputs facilitate at high frequencies.
- raw_fields
{ "n": 21, "doi": "10.1038/ncomms13664", "claim": "In L2/3 of mouse S1, both PV+ and VIP+ interneurons monosynaptically inhibit Martinotti (SST+) cells but with distinct properties: connection probability ~58% PV→MC vs ~35% VIP→MC; mean IPSC amplitude PV 456.55±43.22 pA vs VIP 275.70±46.59 pA; PV→MC inputs depress while VIP→MC inputs facilitate at high frequencies.", "title": null, "cite_key": "Walker2016", "evidence": "Optogenetic ChR2 activation + paired whole-cell recordings of PV→MC and VIP→MC pairs in L2/3 S1.", "effect_size": "Pcon: PV→MC 12/21 (58%), VIP→MC 11/31 (35%); IPSC amplitude PV 456.55±43.22 pA, VIP 275.70±46.59 pA; PV depressing, VIP facilitating at high freq.", "text_access": "fulltext", "study_system": "mouse S1 L2/3 slice", "_source_cluster": "cluster_05_synaptic_connectivity", "replication_status": "replicated", "_source_cluster_index": 23, "claim_source_sentence": "The connection probability was higher for PV cells (∼58%, 12/21) than for VIP cells (∼35%, 11/31) ( ).", "replication_evidence_dois": [ "10.1038/nn.3446" ], "effect_size_source_sentence": "PV cells evoked multicomponent IPSC with apparently larger amplitudes (PV: 456.55±43.22 pA; VIP: 275.70±46.59 pA; mean±s.e.m.) ( )." }- source_refs
[ "paper:paper-e93955349823" ]
- evidence_refs
[ { "ref": "paper:paper-e93955349823" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }