- raw_fields
{
"n": null,
"doi": "10.1038/s41586-021-03969-3",
"claim": "Cellular anatomy of the human cortex resolved by single-nucleus transcriptomics identifies multiple VIP/LAMP5/SNCG interneuron subtypes; connectivity inferred via shared molecular markers.",
"title": null,
"cite_key": "Booeshaghi2021",
"evidence": "Here, in a comprehensive analysis of 6,160 mouse primary motor cortex cells assayed with SMART-seq, 280,327 cells assayed with MERFISH<sup>2</sup> and 94,162 cells assayed with 10x Genomics sequencing<sup>3</sup>, we find examples of isoform specificity in cell types-including isoform shifts between cell types that are masked in gene-level analysis-as well as examples of transcriptional regulation.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "Mouse/rat/human cortex or hippocampus, see paper",
"_source_cluster": "cluster_05_synaptic_connectivity",
"replication_status": "replication_unknown",
"_source_cluster_index": 279,
"claim_source_sentence": "Here, in a comprehensive analysis of 6,160 mouse primary motor cortex cells assayed with SMART-seq, 280,327 cells assayed with MERFISH<sup>2</sup> and 94,162 cells assayed with 10x Genomics sequencing<sup>3</sup>, we find examples of isoform specificity in cell types-including isoform shifts between cell types that are masked in gene-level analysis-as well as examples of transcriptional regulation.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-9443e876ca93"
]
- source_span
Here, in a comprehensive analysis of 6,160 mouse primary motor cortex cells assayed with SMART-seq, 280,327 cells assayed with MERFISH<sup>2</sup> and 94,162 cells assayed with 10x Genomics sequencing<sup>3</sup>, we find examples of isoform specificity in cell types-including isoform shifts between cell types that are masked in gene-level analysis-as well as examples of transcriptional regulation.
- evidence_refs
[
{
"ref": "paper:paper-9443e876ca93"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}- evidence_summary
Here, in a comprehensive analysis of 6,160 mouse primary motor cortex cells assayed with SMART-seq, 280,327 cells assayed with MERFISH<sup>2</sup> and 94,162 cells assayed with 10x Genomics sequencing<sup>3</sup>, we find examples of isoform specificity in cell types-including isoform shifts between cell types that are masked in gene-level analysis-as well as examples of transcriptional regulation.